Lenvatinib (CAS: 417716-92-8) CAS NO.417716-92-8

956958-53-5
Lenvatinib
4-[3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamide

Test Item	Analysis Specification	Result
Description	crystalline powder	Conforms
Melting range	129°C~132°C	131C
Loss on drying	≤0.5%	0.10 %
Specific rotation	-58°~-62°(C=1,in CH3OH)	-61.05°
Sulphated ash	≤0.1%	0.04 %
Heavy metals	≤10ppm	Conforms
Chlorides	≤0.02%	Conforms
Sulfates	≤0.02%	Conforms
Fluorine	14.7%~17.9%	15.2%
Residual solvent	Methanol ≤0.2% Isopropanol ≤0.2% Ethyl acetate≤0.2% Chloroform ≤0.2%	0.0% 0.0% 0.0% 0.0%
Related substances (HPLC)	Single impurity ≤0.2% Total impurities ≤0.5%	0.05% 0.08%
Assay	≥99.5%	99.99%
Conclusion	Accordance with the in house standard

Product name	Lenvatinib
CAS NO.	417716-92-8
Synonyms	Lenvatinib
Category	Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Standard	purity:>99%
Appearance	Lenvatinib powder
Shelf life	2 years
Usage	Lenvatinib is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.
Storage	Lenvatinib should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.